Penetration of Cefazolin into Pleural Fluid

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Penetration of cefazolin into pleural fluid.

Single doses of cefazolin, 500 mg intramuscularly and 1 g intravenously, were administered to 16 patients having lung pathology who were scheduled for thoracic fluid aspiration. Pleural fluid and serum samples were taken at intervals of 30 to 240 min for determination of cefazolin levels. The levels obtained were variable; however, the levels of cefazolin in pleural fluid generally exceeded the...

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Penetration of cefazolin, cephaloridine, and cefamandole into interstitial fluid in rabbits.

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Contact details for the corresponding author: 14 Ioannis Kioumis 15 Associate Professor in Pulmonology and Infectious Diseases 16 Department of Pulmonary Medicine, Aristotle University of Thessaloniki 17 G. Papanikolaou Hospital 18 Exochi 57010, Thessaloniki 19 Greece 20 AAC Accepts, published online ahead of print on 9 December 2013 Antimicrob. Agents Chemother. doi:10.1128/AAC.02291-13 Copyri...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1977

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.11.6.1033